The activation of the adenosine A2A receptor, which is mediated by the inhibition of adenosine A1 receptor, has been associated with depression-like behavior and anhedonia. High levels of cortisol, ...

Talking about the thing most often found in drinks like coffee and teas, he explains: "Caffeine keeps you alert by blocking adenosine receptors. Because it shares a similar shape to adenosine ...

Here’s why. You may feel sleepy after drinking coffee because caffeine blocks adenosine receptors in the brain. Adenosine is an important brain chemical that impacts our sleep-wake cycles.

Caffeine boosts alertness as it blocks adenosine receptor activity, which promotes sleepiness. “The inspiration for this study came from previous research carried out in rodents by Robin Dando, which ...

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...