Cholestatic liver diseases (CLDs) are a group of disorders characterized by the impairment of bile formation, secretion, or excretion. This impairment leads to bile acid accumulation in the liver ...

This study examined the natural history of infants born with alpha-1 antitrypsin (AAT) deficiency and liver disease ... by too few bile ducts resulting in cholestasis, can damage not only the ...

Cholestatic liver diseases, including primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), are conditions characterized by impaired bile flow, leading to liver damage and ...

However, disruptions in bile acid metabolism can lead to cholestatic liver diseases, where bile flow is impaired, resulting in the accumulation of bile acids in the liver and bloodstream.

Announcing a new publication for Acta Materia Medica journal. Estrogens have been reported to cause dysfunction in biliary transport systems, thereby inducing cholestasis. Multidrug ...

The results of the patient's liver function tests were normal when incontinence was diagnosed and her medical history was not remarkable for any other diseases, drug addiction, alcohol abuse or ...

Overall, these findings illustrate that miR-128-3p inhibits PDZK1 expression, thereby inhibiting the membrane localization of MRP2 in EIC. Enhancing or restoring PDZK1 expression might therefore have ...

Announcing a new publication for Acta Materia Medica journal. Estrogens have been reported to cause dysfunction in biliary transport systems, thereby inducing cholestasis. Multidrug ...

Cholestasis of pregnancy (also known as ... common in women carrying multiples and in women with a history of liver damage or disease. "This is my third pregnancy and I was told I was going ...

inhibitor approved by the U.S. Food and Drug Administration for two pediatric cholestatic liver diseases. It is approved for the treatment of cholestatic pruritus in patients with Alagille ...

The differential diagnosis of drug-related liver injury should include all ... was suspected because of the onset of the disease, a cholestatic acute hepatitis, and the age and gender of the ...