An investigation of the structural assembly between receptors involved in dimerization showed that there are several sites of interaction including hydrophobic transmembrane domain interactions ...

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

The ligand binds to a site in the extracellular domain of the receptor (not shown) and induces a conformational change that activates the cytoplasmic domains, enabling interaction and assembly of ...