whereas D2-like receptors, D2, D3 and D4, mediate dopamine inhibition of adenylyl cyclase. In this report, we present observations on the agonist-mediated regulation of the monomeric and ...

It's an N-methyl-D-aspartate (NMDA) receptor inhibitor that works by blocking dopamine reuptake and increasing dopamine ...

Findings could lead to new treatments for dopamine transporter-related disorders and addiction to drugs such as cocaine, ...

serotonin–norepinephrine reuptake inhibitors, noradrenergic and specific serotonin receptor antagonists, dopamine and norepinephrine reuptake inhibitors, along with newly introduced ...

Antagonism of dopamine-mediated inhibition of cAMP accumulation in C-6 cells transfected with D 2L receptors was performed as follows. Cells were plated in 24 well tissue culture dishes and grown ...

“The end game is trying to relate [dopamine signaling] back to schizophrenia and other disorders with working memory impairment,” study coauthor Joshua Roffman of MGH and Harvard University told The ...

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

Their findings, published in Nature Neuroscience, suggest that different aspects of reward-related behavior are supported by two distinct dopamine receptors, namely D3 and D1. "The previous ...

Mounting evidence indicates the short half-life of levodopa and resultant pulsatile stimulation of striatal dopamine receptors leads ... A dopa decarboxylase inhibitor (DDCI), such as carbidopa ...

Chemogenetic activation of VTA DA neurons in males enhanced male preference, while inhibition ... dopamine pathways adjusted their social preferences, enhancing activity through D1 receptors ...