A progressive liver condition affects thousands of Americans, but early symptoms are often dismissed as everyday ailments.

PBC is a chronic, autoimmune disease in which ... with its prevalence on the rise. Symptoms include debilitating fatigue and itching (pruritus), and it can worsen over time if not effectively ...

However, research on quality-of-life outcomes in patients with PBC suggests that effectively managing the condition requires more than simply watching lab values. Studies have shown that symptoms ...

one of the most debilitating symptoms of PBC – with the PPAR delta agonist. The results are good news for Gilead, which acquired seladelpar as part of its $4.3 billion takeover of CymaBay ...

Primary billiary cholangitis, or PBC, is a chronic disease that gradually damages the bile ducts, and eventually your liver. You may also hear it called primary billiary cirrhosis. Your bile ducts ...

People with PBC usually have a buildup of bile in their body. You may have no symptoms or you may have fatigue or itching. Over time, you may develop more serious symptoms due to the buildup of ...

Affecting approximately 25,000 people in the UK, PBC is a rare autoimmune disease of the bile ducts that mainly affects women and currently has no cure. Pruritus, or chronic itch, and fatigue are ...

Primary biliary cirrhosis (PBC) is a chronic, cholestatic liver disease characterized by progressive destruction of intrahepatic bile ducts, resulting in chronic cholestasis, portal inflammation ...

The association between celiac disease and primary biliary cirrhosis is well established. The breakdown of gut–liver axis equilibrium plays a central role in the development of immune disorders ...