B-cell maturation antigen, or BCMA, is selectively expressed when plasma cells differentiate. It is almost absent on memory and naive B cells. The maintenance of long-lived plasma cells involves ...

Chronic lymphocytic leukemia (CLL) is a B-cell malignancy, with disease progression ranging from slow and indolent to ...

Table 1 Strategies for therapeutic targeting of B cells and plasma cells in SLE * Full size table Figure 2: Strategies for B-cell targeting in SLE. Strategies that target B cells will be discussed ...

Activated, autoreactive T cells predominate in mild lesions, but autoreactive B cells and plasma cells outnumber them in severe lesions. Many patients with pSS are treated only to relieve the ...

Plasma cells (PCs) are the terminal differentiation stage of activated B cells and serve as crucial effector cells in humoral immunity. While PCs have ...