Primary hypogonadism (hypergonadotropic hypogonadism) occurs when the hormone deficiency is due to problems in the sex glands, or gonads—the female ovaries and male testes.

Normosmic idiopathic hypogonadotropic hypogonadism (IHH) and Kallmann syndrome are rare congenital forms of secondary hypogonadism characterized by delayed or absent sexual development.

Factors associated with severe deficits included ... In addition, conditions associated with low BMD, such as GHD or hypogonadism, "are also treatable." Ness and colleagues concluded that ...