Whether it's rum, Everclear, vodka, or bourbon, determining how many shots are in a 750-milliliter bottle of liquor (also known as a "fifth") depends on how you define "a shot." American consumers ...
For example, shots of liqueurs or aperitifs with a lower ABV can be larger than the standard amount. If you stick to the 1.5-ounce measurement, a 750 ml bottle should give you 17 shots.