Medscape10h
CAR T-Cell Therapy Safe in Those With Autoimmune Disease
CAR T-cell therapy for cancer leads to similar safety and cancer outcomes in patients with and without preexisting autoimmune ...
Pfizer’s Adcetris combination regimen approved by FDA for r/r DLBCL
Pfizer (PFE) announced that the U.S. FDA has approved the supplemental Biologics License Application for ADCETRIS in combination with ...
Oncology Nurse Advisor5h
Research Suggests Caregivers Could Benefit from Extra Support During CAR-T Therapy
Interviews revealed what patients and their caregivers focus on and needed support throughout the CAR-T therapy trajectory.
Medscape2d
Promise for CAR T-Cell Therapies in Solid Tumors?
CAR T-cell therapies have demonstrated efficacy in treating blood cancers but, so far, their safety and effectiveness in ...
Study reveals mechanism behind car molecule transfer in cancer therapy
Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...
Science Daily23h
Gene modification could improve cancer treatment's success rate
A research team has made a major discovery on how the CUL5 gene affects CAR-T cell therapy, an advanced cancer therapy. The study reveals that reducing the activity of the CUL5 gene helps CAR-T cells ...
The New England Journal of Medicine7d
CD4+ T-Cell Lymphoma Harboring a Chimeric Antigen Receptor Integration in TP53
Malignant T-cell transformation after chimeric antigen receptor (CAR) T-cell therapy has been described, but the contribution of CAR integration to oncogenesis is not clear. Here we report a case ...