An investigation of the structural assembly between receptors involved in dimerization showed that there are several sites of interaction including hydrophobic transmembrane domain interactions ...
Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599-7365, United States ...
dDepartment of Molecular Brain Science, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, Japan eLaboratory for Molecular Mechanisms of Brain Development, RIKEN Center for ...
This study uses state-of-the-art methods to label endogenous dopamine receptors in a subset of Drosophila mushroom body neuronal types. The authors report that Dop1R1 and Dop2R receptors, which have ...
We harnessed optogenetic tagging to record from striatal D2-dopamine receptor-expressing medium spiny neurons (D2-MSNs) in the indirect pathway and from D1-dopamine receptor-expressing MSNs (D1-MSNs) ...
In addition, genes for certain dopamine receptors, and enzymes that metabolize dopamine, may be affected in individuals with ADHD. Dopamine’s action in the brain Two dopamine pathways implicated ...
As a result, this study aimed to explore the involvement of dopamine D2 receptor (D2R) expressing neurons located in the nucleus accumbens (NAc), a critical nucleus governing sleep-wake regulation, in ...
This was confirmed using haloperidol, in a dose that blocks both dopamine D1 and D2 receptors, as it inhibits the effect of dopamine on glucose uptake. Bromocriptine-induced glucose uptake in the ...
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