CD4 T helper cells are a type of white blood cell called a lymphocyte that serves an important role in your immune system. These cells help defend the body against infection by directing other ...

Most HIV-negative adults have between 500 and 1500 CD4 cells in a cubic millimeter of blood. However, due to natural variation some people may have a CD4 count slightly outside the general range. It ...

Two research teams led by Warner Greene at the Gladstone Institutes in San Francisco have demonstrated that the vast majority of CD4 T cells in lymphoid tissues, despite their ability to resist full ...

Most HIV-negative adults have between 500 and 1500 CD4 cells in a cubic millimeter of blood. Most people with HIV who have an undetectable viral load can reach the normal range and often it is only a ...

The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

S3). Immunohistochemical analysis showed a dense lymphocytic infiltration of the lamina propria positive for T-cell receptor (TCR) α, CD3, CD4, and granzyme B but which did not express TRBC1 ...

Here we have designed a CAR, CD4CAR, which redirects the antigen specificity of CD8+ cytotoxic T cells to CD4-expressing cells. CD4CAR T cells derived from human peripheral blood mononuclear cells ...