Pitavastatin is a novel statin that induces plaque regression and is non-inferior to atorvastatin and ... Both the pitavastatin molecule and the lactone metabolite undergo very little metabolism ...

When you first enter a new world, you can either spawn near a structure or find one while exploring any of the three dimensions. While finding some can be quite easy, others are extremely hard to ...

AT and its five metabolites, namely, 2-hydroxy atorvastatin (2-AT), 4-hydroxy atorvastatin (4-AT), atorvastatin lactone (ATL), 2-hydroxy atorvastatin lactone (2-ATL), and 4-hydroxy atorvastatin ...

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

Background: Statins are generally well tolerated, but some patients discontinue therapy secondary to adverse effects. Dosing a statin (rosuvastatin) every other day (EOD) may provide significant ...

Zocor (simvastatin) and Lipitor (atorvastatin) are both statin drugs, which are medications used to lower cholesterol levels in the blood. Statins primarily work by inhibiting the enzyme HMG-CoA ...

Research is unclear on whether CoQ10 supplements can help your heart health or help relieve muscle pain from statin medications. Your doctor can best determine if you may benefit from taking both ...

Can include rhythm, melody, harmony, dynamics, texture, timbre and structure. of the music such as their melody close melodyDifferent pitched notes played one after another making a tune., ...

A variety of organisms, such as bacteria, fungi, and plants, produce secondary metabolites, also known as natural products. Natural products have been a prolific source and an inspiration for numerous ...

Department of Chemistry, Stanford University, 337 Campus Drive, Stanford, California 94305, United States ...

Department of Chemistry, Chung Yuan Christian University, Chung-Li 320314, Taiwan ...

[1] Therapeutic strategy of biological macromolecules based natural bioactive compounds of diabetes mellitus and future perspectives: A systemic review ...