A key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T cell. Dysregulated CD4 T cells have been implicated in autoimmune liver disease ...

This article explains what CD4 T cells are, their role in HIV infection, and how they are involved in the diagnosis and treatment of HIV. Related: How the Immune System Works T cells are a subset ...

Whereas prior acute GVHD impaired Treg reconstitution, Treg subsets (absolute numbers and frequencies relative to CD4 + T-cell subsets) at 3, 6 and 12 months after HSCT were not associated with ...

For more information, refer to the full study in Nature Communications.

This study aimed to investigate the dynamics of peripheral blood T lymphocyte subsets during peginterferon alpha (peg-IFN-α) therapy and their association with hepatitis B surface antigen (HBsAg ...

The differentiation of CD4 T cells into T helper 1 (TH1) or T follicular helper (TFH) subsets is often critical for controlling tumors, while their transformation into regulatory T cells (Tregs ...

People whose CD4 T-cell count remains below 200 or even 350 are more prone to AIDS-related events and non-AIDS infections.