Cholestatic liver diseases, including primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), are conditions characterized by impaired bile flow, leading to liver damage and ...

However, disruptions in bile acid metabolism can lead to cholestatic liver diseases, where bile flow is impaired, resulting in the accumulation of bile acids in the liver and bloodstream.

Announcing a new publication for Acta Materia Medica journal. Estrogens have been reported to cause dysfunction in biliary transport systems, thereby inducing cholestasis. Multidrug ...

Professor Dr Mohamed Rela, a world-renowned liver transplant surgeon, joins King’s College Hospital Dubai to lead the paediatric liver transplant team, enhancing advanced liver transplant services in ...

Overall, these findings illustrate that miR-128-3p inhibits PDZK1 expression, thereby inhibiting the membrane localization of MRP2 in EIC. Enhancing or restoring PDZK1 expression might therefore have ...

Announcing a new publication for Acta Materia Medica journal. Estrogens have been reported to cause dysfunction in biliary transport systems, thereby inducing cholestasis. Multidrug ...

Bile duct disorders can lead to serious complications if left untreated, but early diagnosis and proper management can ...

Fat-soluble vitamins (FSV) are also malabsorbed in cholestasis, and regular supplementation ... an ideal feed for infants with liver disease would be a palatable (whole protein) formula with ...

Treatment of this autoimmune liver disease should also address various symptoms and complications arising from any associated autoimmune diseases, particularly cholestasis and cirrhosis-related ...

Dysbiosis in the Gut-Liver Axis Drives Bone Loss during Cholestatic Liver Disease. The Liver Scholar Award is designed to provide exceptional young investigators committed to pursue a career in ...

(Nasdaq: MIRM) today announced that on February 10, 2025, the Compensation Committee of Mirum’s Board of Directors granted ...