Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

WWP1 demonstrates a dual function, acting predominantly as an oncogene in tumors but occasionally as a tumor suppressor. This review summarizes ... and associated signaling pathways in human cancers ...

This study reveals the underlying mechanism, involving a human non-coding RNA-encoded micropeptide (hSPAR) as a novel dual regulator of mTORC1 assembly and tumor growth. Micropeptide hSPAR is a tumor ...

The UTC human cell line ARO was kindly provided by ... Histological preparations were made from the tumor, lung, liver, skin, and thyroid. The tissues were fixed with 10% buffered formol (pH ...

The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

Most cells in the body have two sets of 23 chromosomes (one set of chromosomes comes from each parent). Cancers can be caused by changes in chromosomes that turn on oncogenes or turn off tumor ...

Background: Liquid biopsies combine minimally invasive sample collection with sensitive detection of residual disease. Pediatric malignancies harbor tumor-driving copy number alterations or fusion ...