We previously introduced the concept of 'oncogene addiction' to explain how some cancers that contain multiple genetic, epigenetic, and chromosomal abnormalities are dependent on or 'addicted' to ...

serving as a foundation for the now widely accepted phenomenon called oncogene addiction 11. But the euphoria of blast-crisis remissions was short lived. Despite continued imatinib treatment ...

In view of this complexity, how can we identify the specific oncogene or oncogenes that have a critical role in maintaining the malignant phenotype in these different cancer types, or within ...