With Deebo Samuel's time in San Francisco appearing to wind down, star tight end George Kittle spoke on how the 49ers offense will have to adjust without the dynamic wide receiver.

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Matt Maiocco highlights that something seemed off about San Francisco 49ers wide receiver Deebo Samuel's demeanor this past season.

The 49ers have given Deebo Samuel permission to seek a trade. George Kittle believes San Francisco will have trouble replacing him.

The 49ers have given wide receiver Deebo Samuel permission to talk to teams that might be interested in trading for him this offseason and that is likely the first step toward Samuel's departure after six seasons with the team.

The San Francisco 49ers face a unique challenge when considering Deebo Samuel’s future. His playmaking ability and versatility make him more than just another offensive player. He’s a dynamic weapon who brings a distinctive element that’s hard to match elsewhere in the NFL.

George Kittle appeared on USA Today’s Sports Seriously and said this about the former South Carolina receiver: “You can’t really replace Deebo. I think he’s one of the most unique players in the NFL because of what he can do.

While Deebo Samuel’s future with the 49ers remains uncertain, Kittle's remarks highlight both the challenge of moving forward without him and the optimism surrounding the team’s offensive weapons heading into the 2025 season.